WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and to clarify the associated molecular mechanism. Our study shows that rhein in combination with PTX could obviously increase the systemic exposure of PTX in rats, which would be … WebbOrganic anion transporters play important roles in the elimination of a variety of endogenous substances, xenobiotics and their metabolites from the body. During the …
Frontiers Symbiosis preservation: Putative regulation of fatty acyl …
WebbOrganic anion transporters (OATs) are shown in red, the organic cation/carnitine transporter (OCTN/CT) family is shown in blue, and organic cation transporters (OCTs) … Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the Solute Carrier Family (SLC) and the major facilitator superfamily. ekg changes pulmonary hypertension
In Vitro and In Vivo Evidence of the Importance of Organic Anion ...
WebbSeveral families of multispecific organic anion and cation transporters, including OAT family transporters, have recently been identified by molecular cloning. The OAT family … Webb9 juni 2010 · The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys and … Webbscientific article ekg changes in pregnancy