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Tff1-creert2

Web图 1 Tff1 CreERT2/+; Rosa26 tdTomato/+ 小鼠胃粘膜上皮细胞中tdTomato的表达情况。 经Tamoxifen诱导后,Tff1 CreERT2/+; Rosa26 tdTomato/+ 双转基因鼠,可在小鼠胃粘膜 … Web1 Dec 2024 · Using a stomach-specific CreERT2 system, we created mice that develop tumors with morphologic similarities to subtypes of human gastric cancer. ... TFF1 is …

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WebAccepted Article Thiem et al. Murine model for gastric-specific gene modifications Inducible gene modification in the gastric epithelium of Tff1-CreERT2;Tff2-rtTA;Tff3-Luc mice Stefan Thiem 1*, Moritz F. Eissmann , Emma Stuart 2, Joachim Elzer 1, Anna Jonas 3, Michael Buchert and Matthias Ernst 1, # 1 Cancer and Inflammation Laboratory, Olivia Newton … space manchester https://highland-holiday-cottage.com

Inducible gene modification in the gastric epithelium of …

WebDownload scientific diagram Mast cell depletion reduces macrophage infiltration in gastric tumors of gp130FF mice. a Representative images of tissue sections immunostained for macrophages... Web11 May 2024 · Studies using a transgenic Tff1-CreERT2 model (tamoxifen-inducible Cre recombinase) revealed rare tracing of SMCs in the fundic units, reflecting the distribution of endogenous Tff1 protein [143,144]. In contrast, about 20% of the antral units stained entirely positive, indicating that recombination also occurred in stem cells [143,144]. WebTff1-2A-CreERT2, Tff1 em1(2A-CreERT2-polyA)Smoc: Gene: Tff1 Location: Chr17:31380369-31384034 bp, - strand Genetic Position: Chr17, 15.8 cM Alliance: Tff1 em1(cre/ERT2)Smoc page Mutation origin: Strain of Origin: C57BL/6J: Mutation description: Allele Type: Endonuclease-mediated (Inducible, Recombinase) Inducer: spaceman ceramic night light

Tg (Tff1-cre/ERT2,Tff2-rtTA,Tff3-luc)#Ern - MGI-Mouse …

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Tff1-creert2

Profiling trefoil factor family (TFF) expression in the mouse ...

Web25 Oct 2016 · Therefore, the Tg(Tff1-CreERT2;Tff2-rtTA;Tff3-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous … WebFor in-depth product & services help, ask our Technical Information Scientists

Tff1-creert2

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WebThe Tg(Tff1-CreERT2;Tff2-rtTA;Tff3-Luc) strain confers tamoxifen-inducible irreversible somatic recombination and allows simultaneous doxycycline-dependent reversible gene … Web31 Aug 2024 · Lineage tracing studies using transgenic Tff1-CreERT2 and Tff1-Cre mice showed that Tff1 is also expressed in long-lived stem and progenitor cells of the gastric …

Web2 Feb 2016 · The resulting Tg (Tff1-CreERT2) mice were crossed with mice harboring conditional oncogenic mutations in Kras or Braf The administration of tamoxifen to the … Web1 Dec 2024 · Using a stomach-specific CreERT2 system, we created mice that develop tumors with morphologic similarities to subtypes of human gastric cancer. These tumors have different patterns of local growth, metastasis, and response to therapeutic agents. They can be used to study different subtypes of human gastric cancer. Graphical abstract

WebExpression of TFF1 protein was checked in 52 paraffin-embedded tissues of BCs by immunochemistry, and serum concentration of TFF1 in 70 BC patients and 32 healthy controls was measured by ELISA. Functional activities of TFF1 in BC cells were determined by CCK-8 assay, colony formation, BrdU-DNA synthesis, and assays for migration and … Web1 Nov 2024 · To target this molecule, trastuzumab, a monoclonal antibody against HER2, was developed and has been shown in the ToGA trial to be efficacious as a frontline treatment for gastric cancer when combined with multiagent chemotherapy [ 39 ]. Multiple other HER2 targeting agents and strategies have not shown clinical efficacy [ 11 ].

Web图 1 Tff1 CreERT2/+; Rosa26 tdTomato/+ 小鼠胃粘膜上皮细胞中tdTomato的表达情况。 经Tamoxifen诱导后,Tff1 CreERT2/+; Rosa26 tdTomato/+ 双转基因鼠,可在小鼠胃粘膜 …

Web31 Jan 2024 · Tg (Tff1-cre/ERT2,Tff2-rtTA,Tff3-luc)#Ern Transgene Detail MGI Mouse (MGI:5911344) Search All Search Tools Genes Genes & Markers Query Batch Query … teams off screenWeb26 Sep 2024 · Tff2 is a candidate gene controlling pulmonary function in mice. Spasmolytic polypeptide/trefoil factor family 2 (TFF2)-expressing metaplasia (SPEM)was immunoreactive for TFF2, Mist1 and intrinsic factor, suggesting that SPEM derived from transdifferentiation of chief cells. teams of horses for sale albertaWeb16 Sep 2024 · Here, they play different roles for mucosal protection and the innate immune defense: TFF1 is a gastric tumor suppressor; TFF2 builds a lectin complex with the mucin … teams offreWebInducible gene modification in the gastric epithelium of Tff1-CreERT2, Tff2-rtTA, Tff3-luc mice. Authors: Stefan Thiem Moritz F Eissmann Emma Stuart Joachim Elzer Anna Jonas … teams off shift access controlWebThe resulting Tg (Tff1-CreERT2) mice were crossed with mice harboring conditional oncogenic mutations in Kras or Braf. The administration oftamoxifen to the resulting adult … spaceman ice cream machine for saleWeb@article{Hertel2004ProfilingTF, title={Profiling trefoil factor family (TFF) expression in the mouse: identification of an antisense TFF1-related transcript in the kidney and liver}, author={Silvia C. Hertel and Caroline E. Chwieralski and Margitta Hinz and M. C. Rio and Catherine Tomasetto and Werner Hoffmann}, journal={Peptides}, year={2004 ... spaceman helmet vectorWebOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life. On Dec 16, 2024, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license ... spaceman johan renck