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Olfm4 and cancer

WebOLFM4 expression has been studied in several tumor types including gastric, colorectal, lung, and endometrioid cancers where it has been suggested to be an independent … Web10. apr 2024. · Gastric cancer is a dominant source of cancer-related death around the globe and a serious threat to human health. However, there are very few practical diagnostic approaches and biomarkers for the treatment of this complex disease. ... SFRP4, CDH17, FAP, CLDN1, and OLFM4 were of the highest LogFC values among the upregulated …

P16、OLFM4在宫颈上皮内瘤变中的表达及其诊断意义.docx-原创 …

WebOlfactomedins (OLFMs) are a family of glycoproteins that play a relevant role in embryonic development and in some pathological processes. Although OLFM2 is involved in the regulation of the energy metabolism and OLFM4 is an important player in inflammation, innate immunity and cancer, the role of OLFMs in NAFLD-related intestinal dysbiosis … Web24. mar 2024. · OLFM4 is secreted and may be detected in serum and plasma therefore representing a good candidate CRC marker as previously suggested for gastric cancer [35, 36]. Sec24C is an essential coat protein II (COPII) component and COPII is involved in protein transports from the endoplasmic reticulum (ER). prince from snow white disney https://highland-holiday-cottage.com

OLFM4 Enhances STAT3 Activation and Promotes Tumor …

Web02. maj 2024. · OLFM4 promotes tumor cell proliferation by activating STAT3 and accelerating cell-cycle progression in gastric cancer 22 and pancreatic cancer. 25 … Web02. maj 2024. · Moreover, the cancer stem cell-like property of OLFM4 mediated by leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5), known as an intestinal stem … WebChronic inflammatory bowel disease (IBD) is strongly associated with the development of colitis-associated tumorigenesis (CAT). Despite recent advances in the understanding of … prince from snow white name

Olfactomedin 4 deletion induces colon adenocarcinoma in

Category:OLFM4 deficiency delays the progression of colitis to colorectal cancer …

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Olfm4 and cancer

OLFM4 Antibody, Biotin conjugated - cusabio.cn

Web03. apr 2012. · Human olfactomedin 4 (OLFM4) gene is a secreted glycoprotein more commonly known as the anti-apoptotic molecule GW112. OLFM4 is found to be frequently up-regulated in many types of human tumors including gastric cancer and it was believed to play significant role in the progression of gastric cancer. Although the function of OLFM4 … Web15. mar 2024. · Low expression of OLFM4 promoted lymph node and distant metastasis resulting in a poor prognosis of triple-negative breast cancer patients and low expression of OLFM4 in early gastric cancer was ...

Olfm4 and cancer

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Web01. jun 2016. · Development of colorectal cancer (CRC) is regulated by a series of genetic and microenvironmental alterations. Olfactomedin 4 (OLFM4) is a secreted glycoprotein that is highly expressed in the ... WebNational Center for Biotechnology Information

Web13. maj 2016. · OLFM4 expression is correlated with cancer differentiation, stage, metastasis, and prognosis in a variety of cancers, suggesting its potential clinical value … WebPancreatic ductal adenomcarcinoma (PDAC) is one of the most lethal forms of cancer with a 5-year survival rate of 8%. To determine the composition of different cell types in PDAC, we performed ...

Web09. feb 2024. · INTRODUCTION. Pancreatic ductal adenocarcinoma (PDAC) has recently surpassed breast cancer to become the third leading cause of cancer-related mortality according to the American Cancer Society, with a 5-year survival in the single digits [].Despite improvements in surgical techniques and adjuvant chemoradiotherapy, the … Web目的 研究P27kipl和CyclinA蛋白在胃癌中的表达,探讨其在胃癌发生、发展中的可能作用及意义。方法 应用免疫组化S-P法检测P27kipl和CyclinA蛋白表达情况。结果 P27kipl和CyclinA蛋白在62例胃癌中表达阳性率分别为27.4％和41.9％;58例癌前病变中分别为44.8％和22.4％;25例正常对照组中分别为84.0％和0.0％,胃癌与癌前 ...

Web02. maj 2024. · Conclusion: OLFM4 is induced by the LGR5-Wnt signaling pathway and is strongly associated with aggressive tumor progression and poor prognosis in HCC by regulating STAT3-induced tumor cell proliferation and cancer stem cell–like property. Therefore, OLFM4 is a novel prognostic predictor and a potential therapeutic target for …

Web01. jun 2016. · Development of colorectal cancer (CRC) is regulated by a series of genetic and microenvironmental alterations. Olfactomedin 4 (OLFM4) is a secreted glycoprotein … prince from the come up miamiWeb28. sep 2010. · The OLFM4 gene was first identified by virtue of its high expression in colon cancer cells through analysis of Cancer Genome Anatomy Project data from the United States National Cancer Institute. The gene was originally cloned from human haematopoietic myeloid cells and mapped to chromosome 13q14.3 [].It consists of five … prince from snow white costumeWeb01. mar 2024. · The olfactomedin 4 (OLFM4) gene has been analyzed as a tumor-suppressor gene and a putative biomarker in many cancers. In our study, we analyzed … pld to cnyWeb27. feb 2024. · A Data Scientist with pre-Sales Experience. Proven success in delivering transformational, never done before AI wins across the region, in both a startup and a large complex organization. A developer at heart but with an eye for practical AI and creating impact with technology. I’m a co-author of multiple Cancer publications and hold a MSc … prince from spaceballsWeb10. jan 2024. · Chemoresistance was observed by in vitro analysis of tumor cell lines with forced expression of OLFM4. In an assessment of tissue specimens from 80 patients … prince from sophia the firstWebNational Center for Biotechnology Information prince from the little mermaidWebProtein function (UniProt)i. Useful information about the protein provided by UniProt. May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leu kemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 ... pldt notice today