Lineage transcription factor
Nettet8. jun. 2024 · Lineage transcription factors (TFs), such as SOX10 in melanoma 10, 11, are often needed for cancer cell survival and proliferation 12, 13. However, whether specific interactions between... Nettet9. feb. 2024 · The identity of the cells generated along neurogenesis is determined by the transcriptional programs operating on each cell type. The different gene expression …
Lineage transcription factor
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NettetCell-intrinsic and cell-extrinsic cues regulating lineage decisions in multipotent neural crest-derived progenitor cells. Int J Dev Biol 2002, 46(1):193-200. Pereira, L., Yi, F., Merrill, B. J. (2006). Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal. Mol Cell Biol 2006, 26(20):7479-7491. NettetTranscription factors are proteins that bind to DNA-regulatory sequences (enhancers and silencers), usually localized in the 5 -upstream region of target genes, to modulate the …
Nettet17. des. 2008 · Lineage-specific transcription factors and the evolution of gene regulatory networks Nature is replete with examples of diverse cell types, tissues and … NettetNational Center for Biotechnology Information
Nettet1. jul. 2007 · Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Tom Taghon Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium. Author profile Search articles by ORCID 0000-0002-5781-0288 Taghon T1, Mary A Yui Nettet3. okt. 2013 · Pluripotency-associated factors and their rivals, lineage specifiers, have long been considered the determining factors for the identity of pluripotent and differentiated cells, respectively.
Nettet22. jun. 2006 · Several transcription factors including C/EBPβ, C/EBPδ, ETS1, Menin, Smad1, and Smad5, interact with Runx2 and enhance the transcriptional activity of Runx2. Grg5, Rb, TAZ, and p204 interact with Runx2 and function as transcriptional co-activators of Runx2 [Komori, 2005; Liu et al., 2005 ].
Nettet14. feb. 2024 · Dynamic dysregulation of the counteracting lineage-specific transcription factors (TFs), containing adenomatous TFs NKX2-1 and FOXA2, and squamous TFs … lincoln home beigeNettet16. okt. 2024 · The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune … lincoln hockey clubNettet14. jan. 2024 · Transcription factors associated with T cell development, such as TCF1, TOX, and Bcl11b, are also involved in the generation of ChILPs and the maturation of ILC subsets ( Califano et al., 2015, Seehus et al., 2015, Walker et al., 2015, Yang et al., 2015, Yu et al., 2015). lincoln hitler rick and mortyNettet9. jul. 2024 · Along with the cellular and morphological events that mediate lineage formation in preimplantation embryos, there is a cohort of transcription factors that promote specification of the ICM and TE lineages via molecular mechanisms. These transcription factors can be separated into three subgroups based on their … lincoln hireNettet18. aug. 2024 · During cellular reprogramming, the pioneer transcription factor GATA3 binds chromatin, and in a context-dependent manner directs local chromatin … lincoln hodges attorney germantown tnNettet8. jun. 2024 · As such, this study implicates lineage-specific transcription factors as being the key determinant of tissue-specific cancers caused by mutations. This … lincoln home and garden showNettet2 dager siden · The transcription factors MECOM, PAX8, SOX17 and WT1 are candidate master regulators of high-grade serous 'ovarian' cancer (HGSC), yet their cooperative role in the hypothesized tissue of origin, the fallopian tube secretory epithelium (FTSEC) is unknown. We generated 26 epigenome (CUT&TAG, CUT&RUN, ATAC-seq and HiC) … hotels strasbourg centre