WebHypercalcemia itself can cause reversible nephrogenic diabetes insipidus (NDI) via induction of autophagic degradation of aquaporin 2 channels. Additionally, lithium … WebNational Center for Biotechnology Information

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WebThis condition usually resolves after childbirth. Dipsogenic diabetes insipidus is caused by an abnormality in the thirst mechanism of the brain, leading to excessive fluid intake and production of diluted urine. This condition can be caused by certain medications, psychological factors, or damage to the hypothalamus. WebLithium-induced nephrogenic diabetes insipidus (NDI) is a rare and difficult-to-treat condition. We describe the case of an 81-year-old woman with bipolar treated with lithium and no previous history of diabetes insipidus. She was hospitalized due to disturbance of consciousness and was diagnosed with, hypercalcemia, hyperparathyroidism, and NDI. olpc software download

Diabetes Insipidus - StatPearls - NCBI Bookshelf

WebDehydration, altered mental status, and nephrogenic diabetes insipidus (DI) contributed to the hypercalcemia; calcium levels decreased by 0.25 mmol/l (1 mg/dl) with hydration. … WebNephrogenic diabetes insipidus can be transmitted as an autosomal recessive or autosomal dominant trait. In these cases, the disease is caused by mutations in the AQP2 gene, located on chromosome 12q13. 145,146 To date, 40 different putative disease-causing mutations in the AQP2 gene have been reported in autosomal recessive NDI. … olp customer service