WebThe enzyme FOLH1 is the target for the antibody-based drug Capromab, which is used for diagnosis of prostate cancer and detection of intra-pelvic metastases. FOLH1 has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity and is involved in prostate tumor progression.

PSMA/FOLH1/NAALADase I Products: R&D Systems

WebMar 10, 2024 · Additionally, FOLH1 genetic variation was correlated with neural activity during working memory, as measured by functional MRI (fMRI). Results: A missense mutation in FOLH1 (rs202676 G allele) was associated with increased FOLH1 mRNA in the dorsolateral prefrontal cortex of brains from unaffected subjects and schizophrenia … WebPSMA (prostate-specific membrane antigen) is a type II transmembrane zinc metallopeptidase, belonging to the M28 peptidase family. It possesses hydrolyzing enzyme activities and is also known as FOLH1 (folate hydrolase 1), GCP2 (glutamate carboxypeptidase II), and NAALADase I (N-acetylated-alpha-linked acidic dipeptidase I). 89機車

APC anti-human PSMA FOLH1 Antibody anti-PSMA - LNI-17

WebPSMA/FOLH1/NAALADase I: Products Human prostate-specific membrane antigen (PSMA), a tumor marker in prostate cancer encoded by the FOLH1 gene, is a type II transmembrane zinc metallopeptidase. PSMA is most highly expressed in the nervous system, prostate, kidney, and small intestine. WebPSMA/FOLH1/NAALADase I Products Human prostate-specific membrane antigen (PSMA), a tumor marker in prostate cancer encoded by the FOLH1 gene, is a type II transmembrane zinc metallopeptidase. PSMA is most highly expressed in the nervous system, prostate, kidney, and small intestine. WebThe FOLH1 CRISPR guide RNA sequences shown above were designed by the laboratory of Feng Zhang at the Broad Institute* in order to efficiently target the FOLH1 gene with minimal risk of off-target Cas9 binding elsewhere in the genome. For complete details on the criteria and process for guide RNA design and selection, please see: Sanjana N.E ... 89梗圖